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p21ras is modified by a farnesyl isoprenoid.
Association of oncogenic ras proteins with cellular membranes appears to be a crucial step in transformation, ras is synthesized as a cytosolic precursor, which is processed to a mature form that localizes to the plasma membrane. This processing involves, in part, a conserved sequence, Cys-Ali-Ali-X...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298273/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2682646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8323 |
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