Abl Tyrosine Kinase Phosphorylates Nonmuscle Myosin Light Chain Kinase to Regulate Endothelial Barrier Function

Nonmuscle myosin light chain kinase (nmMLCK), a multi-functional cytoskeletal protein critical to vascular homeostasis, is highly regulated by tyrosine phosphorylation. We identified multiple novel c-Abl–mediated nmMLCK phosphorylation sites by mass spectroscopy analysis (including Y(231), Y(464), Y...

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Detaylı Bibliyografya
Asıl Yazarlar: Dudek, Steven M., Chiang, Eddie T., Camp, Sara M., Guo, Yurong, Zhao, Jing, Brown, Mary E., Singleton, Patrick A., Wang, Lichun, Desai, Anjali, Arce, Fernando T., Lal, Ratnesh, Van Eyk, Jennifer E., Imam, Syed Z., Garcia, Joe G. N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 2010
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982111/
https://ncbi.nlm.nih.gov/pubmed/20861316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-10-0876
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