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State of the art and challenges in sequence based T-cell epitope prediction

Sequence based T-cell epitope predictions have improved immensely in the last decade. From predictions of peptide binding to major histocompatibility complex molecules with moderate accuracy, limited allele coverage, and no good estimates of the other events in the antigen-processing pathway, the fi...

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Bibliografiske detaljer
Main Authors: Lundegaard, Claus, Hoof, Ilka, Lund, Ole, Nielsen, Morten
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981877/
https://ncbi.nlm.nih.gov/pubmed/21067545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-7580-6-S2-S3
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