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Epigenetic and 3-dimensional regulation of V(D)J rearrangement of immunoglobulin genes
V(D)J recombination is a crucial component of the adaptive immune response, allowing for the production of a diverse antigen receptor repertoire (Ig and TCR). This review will focus on how epigenetic regulation and 3-dimensional (3D) interactions may control V(D)J recombination at Ig loci. The inter...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981695/ https://ncbi.nlm.nih.gov/pubmed/20833065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2010.08.002 |
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