Dopamine D4 Receptor Gene Variation Moderates the Efficacy of Bupropion for Smoking Cessation

Smokers (≥10 cig/day; N =331) of European ancestry taking part in a double-blind placebo-controlled randomized trial of 12 weeks of treatment with bupropion plus counseling for smoking cessation were genotyped for a VNTR polymorphism in Exon-III of the Dopamine D4 receptor (DRD4) gene. Generalized e...

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Main Authors: Leventhal, Adam M., David, Sean P., Brightman, Molly, Strong, David, McGeary, John E., Brown, Richard A., Lloyd-Richardson, Elizabeth E., Munafò, Marcus, Uhl, George R., Niaura, Raymond
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981689/
https://ncbi.nlm.nih.gov/pubmed/20661272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2010.64
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