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Infralimbic D2 receptors are necessary for fear extinction and extinction-related tone responses

BACKGROUND: Fear extinction is dependent on plasticity in the infralimbic prefrontal cortex (IL), an area heavily innervated by midbrain dopaminergic inputs. Dopamine D2 receptors are concentrated in infralimbic output neurons that are involved in the suppression of conditioned fear after extinction...

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Main Authors: Mueller, Devin, Bravo-Rivera, Christian, Quirk, Gregory J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981677/
https://ncbi.nlm.nih.gov/pubmed/20926066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.08.014
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