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Tyrosine Phosphatase TpbA Controls Rugose Colony Formation in Pseudomonas aeruginosa by Dephosphorylating Diguanylate Cyclase TpbB

Tyrosine phosphatase TpbA in Pseudomonas aeruginosa PA14 is a negative regulator of the diguanylate cyclase TpbB. Inactivation of TpbA caused rugose colony morphology which is related to cell persistence in clinical infections. We show here that TpbA is a dual specific tyrosine phosphatase, that Tpb...

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Hlavní autoři: Pu, Mingming, Wood, Thomas K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981663/
https://ncbi.nlm.nih.gov/pubmed/20946878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.10.032
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