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Tyrosine Phosphatase TpbA Controls Rugose Colony Formation in Pseudomonas aeruginosa by Dephosphorylating Diguanylate Cyclase TpbB

Tyrosine phosphatase TpbA in Pseudomonas aeruginosa PA14 is a negative regulator of the diguanylate cyclase TpbB. Inactivation of TpbA caused rugose colony morphology which is related to cell persistence in clinical infections. We show here that TpbA is a dual specific tyrosine phosphatase, that Tpb...

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Bibliografiske detaljer
Main Authors: Pu, Mingming, Wood, Thomas K.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981663/
https://ncbi.nlm.nih.gov/pubmed/20946878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.10.032
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