Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans.

Glucokinase, a key regulatory enzyme of glucose metabolism in mammals, provides an interesting model of tissue-specific gene expression. The single-copy gene is expressed principally in liver, where it gives rise to a 2.4-kilobase mRNA. The islets of Langerhans of the pancreas also contain glucokina...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Iynedjian, P B, Pilot, P R, Nouspikel, T, Milburn, J L, Quaade, C, Hughes, S, Ucla, C, Newgard, C B
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298166/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2682629/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.20.7838
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