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Genomic Runs of Homozygosity Record Population History and Consanguinity

The human genome is characterised by many runs of homozygous genotypes, where identical haplotypes were inherited from each parent. The length of each run is determined partly by the number of generations since the common ancestor: offspring of cousin marriages have long runs of homozygosity (ROH),...

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Detalhes bibliográficos
Main Authors: Kirin, Mirna, McQuillan, Ruth, Franklin, Christopher S., Campbell, Harry, McKeigue, Paul M., Wilson, James F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981575/
https://ncbi.nlm.nih.gov/pubmed/21085596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013996
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