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Decrease in Mitochondrial Function in Rat Cardiac Permeabilized Fibers Correlates With the Aging Phenotype

We measured the loss of cardiac mitochondrial function related to aging in males of three rat strains presenting with different longevity and aging phenotypes: the Fischer 344 (F344), the Brown Norway (BN), and the hybrid F344×BN. The F344 rat has a short life span and a ∼45% decrease in coupled mit...

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Detalhes bibliográficos
Main Authors: Lemieux, Hélène, Vazquez, Edwin J., Fujioka, Hisashi, Hoppel, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981518/
https://ncbi.nlm.nih.gov/pubmed/20801909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glq141
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