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Resistance to transforming growth factor β-mediated tumor suppression in melanoma: are multiple mechanisms in place?

Resistance to transforming growth factor (TGF) β-mediated tumor suppression in melanoma appears to be a crucial step in tumor aggressiveness since it is usually coupled with the ability of TGFβ to drive the oncogenic process via autocrine and paracrine effects. In this review, we will focus mainly o...

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Autors principals: Lasfar, Ahmed, Cohen-Solal, Karine A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981460/
https://ncbi.nlm.nih.gov/pubmed/20656791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq155
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