A Functional Cross-Talk between Liver X Receptor-α and Constitutive Androstane Receptor Links Lipogenesis and Xenobiotic Responses

The liver X receptor (LXR) and constitutive androstane receptor (CAR) are two nuclear receptors postulated to have distinct functions. LXR is a sterol sensor that promotes lipogenesis, whereas CAR is a xenosensor that controls xenobiotic responses. Here, we show that LXRα and CAR are functionally re...

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Bibliographische Detailangaben
Hauptverfasser: Zhai, Yonggong, Wada, Tara, Zhang, Bin, Khadem, Shaheen, Ren, Songrong, Kuruba, Ramalinga, Li, Song, Xie, Wen
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2010
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981386/
https://ncbi.nlm.nih.gov/pubmed/20592274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.064618
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