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Further evidence for a maternal genetic effect and a sex-influenced effect contributing to risk for human neural tube defects

BACKGROUND: Neural tube defects (NTDs), including spina bifida and anencephaly, are the second most common birth defect with an incidence of 1/1000. Genetic factors are believed to contribute to NTD risk and family-based studies can be useful for identifying such risk factors. METHODS: We ascertaine...

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Main Authors: Deak, Kristen L., Siegel, Deborah G., George, Timothy M., Gregory, Simon, Ashley-Koch, Allison, Speer, Marcy C.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981339/
https://ncbi.nlm.nih.gov/pubmed/18937341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.20511
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