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Genetic effects of thymine glycol: site-specific mutagenesis and molecular modeling studies.

The mutational specificity and genetic requirements for mutagenesis by 5,6-dihydroxy-5,6-dihydrothymine (thymine glycol), one of the principal DNA lesions induced by oxidation and ionizing radiation, has been investigated in Escherichia coli. Thymine glycol was positioned at a unique site in the sin...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Basu, A K, Loechler, E L, Leadon, S A, Essigmann, J M
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298133/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2682618/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.20.7677
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