Znu Is the Predominant Zinc Importer in Yersinia pestis during In Vitro Growth but Is Not Essential for Virulence

Little is known about Zn homeostasis in Yersinia pestis, the plague bacillus. The Znu ABC transporter is essential for zinc (Zn) uptake and virulence in a number of bacterial pathogens. Bioinformatics analysis identified ZnuABC as the only apparent high-affinity Zn uptake system in Y. pestis. Mutati...

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Detalhes bibliográficos
Main Authors: Desrosiers, Daniel C., Bearden, Scott W., Mier, Ildefonso, Abney, Jennifer, Paulley, James T., Fetherston, Jacqueline D., Salazar, Juan C., Radolf, Justin D., Perry, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981304/
https://ncbi.nlm.nih.gov/pubmed/20855510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00732-10
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