Strong In Vitro Activities of Two New Rifabutin Analogs against Multidrug-Resistant Mycobacterium tuberculosis

Two new rifabutin analogs, RFA-1 and RFA-2, show high in vitro antimycobacterial activities against Mycobacterium tuberculosis. MIC values of RFA-1 and RFA-2 were ≤0.02 μg/ml against rifamycin-susceptible strains and 0.5 μg/ml against a wide selection of multidrug-resistant strains, compared to ≥50...

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Detaylı Bibliyografya
Asıl Yazarlar: García, Ana-Belén, Palacios, Juan J., Ruiz, María-Jesús, Barluenga, José, Aznar, Fernando, Cabal, María-Paz, García, José María, Díaz, Natalia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2010
Konular:
Susceptibility
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981290/
https://ncbi.nlm.nih.gov/pubmed/20855731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00149-10
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