In Vitro Evaluation of Viability, Integrity, and Inflammation in Genital Epithelia upon Exposure to Pharmaceutical Excipients and Candidate Microbicides

The use of microbicides is a promising approach for the prevention of HIV-1 transmission. Unfortunately, various candidates failed in clinical trials. In some cases, the candidate microbicide even resulted in enhanced virus transmission. Therefore, there is an urgent need to develop more predictive...

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Bibliographic Details
Main Authors: Gali, Youssef, Delezay, Olivier, Brouwers, Joachim, Addad, Noura, Augustijns, Patrick, Bourlet, Thomas, Hamzeh-Cognasse, Hind, Ariën, Kevin K., Pozzetto, Bruno, Vanham, Guido
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Analytical Procedures
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981258/
https://ncbi.nlm.nih.gov/pubmed/20921308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00456-10
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