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Binding and Action of CEM-101, a New Fluoroketolide Antibiotic That Inhibits Protein Synthesis
We characterized the mechanism of action and the drug-binding site of a novel ketolide, CEM-101, which belongs to the latest class of macrolide antibiotics. CEM-101 shows high affinity for the ribosomes of Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria. The ketol...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981243/ https://ncbi.nlm.nih.gov/pubmed/20855725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00860-10 |
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