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Coxiella burnetii Expresses a Functional Δ24 Sterol Reductase

Coxiella burnetii, the etiological agent of human Q fever, occupies a unique niche inside the host cell, where it replicates in a modified acidic phagolysosome or parasitophorous vacuole (PV). The PV membrane is cholesterol-rich, and inhibition of host cholesterol metabolism negatively impacts PV bi...

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Autors principals: Gilk, Stacey D., Beare, Paul A., Heinzen, Robert A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981196/
https://ncbi.nlm.nih.gov/pubmed/20870767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00818-10
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