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Survival of Hoxa13 Homozygous Mutants Reveals a Novel Role in Digit Patterning and Appendicular Skeletal Development

The loss of HOXA13 function severely disrupts embryonic limb development. However, because embryos lacking HOXA13 die by mid-gestation, the defects present in the mutant limb could arise as a secondary consequence of failing embryonic health. In our analysis of the mutant Hoxa13(GFP) allele, we iden...

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Main Authors: Perez, Wilma D., Weller, Crystal R., Shou, Siming, Stadler, H. Scott
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981150/
https://ncbi.nlm.nih.gov/pubmed/20034107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22183
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