Herpes simplex virus latent RNA (LAT) is not required for latent infection in the mouse.
During latent infection by herpes simplex virus (HSV), an abundant latency-associated transcript (LAT) that is antisense to a predominant viral alpha gene (ICP0) is found localized in the nucleus of sensory neurons. We disrupted both copies of the LAT gene in the HSV-1 genome by insertion of the Esc...
Salvato in:
| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1989
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2552449/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.19.7596 |
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