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Herpes simplex virus latent RNA (LAT) is not required for latent infection in the mouse.

During latent infection by herpes simplex virus (HSV), an abundant latency-associated transcript (LAT) that is antisense to a predominant viral alpha gene (ICP0) is found localized in the nucleus of sensory neurons. We disrupted both copies of the LAT gene in the HSV-1 genome by insertion of the Esc...

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Dettagli Bibliografici
Autori principali: Ho, D Y, Mocarski, E S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1989
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC298113/
https://ncbi.nlm.nih.gov/pubmed/2552449
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