A Chewable Pediatric Fixed-dose Combination Tablet of Stavudine, Lamivudine, and Nevirapine: Pharmacokinetics and Safety Compared With the Individual Liquid Formulations in Human Immunodeficiency Virus-infected Children in Thailand

BACKGROUND: Pediatric fixed-dose combinations (FDCs) are needed to facilitate antiretroviral therapy in children. We evaluated the relative bioavailability, safety, and therapeutic adequacy of a novel chewable pediatric FDC tablet of stavudine (7 mg), lamivudine (30 mg), and nevirapine (50 mg), refe...

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Hauptverfasser: Vanprapar, Nirun, Cressey, Tim R., Chokephaibulkit, Kulkanya, Muresan, Petronella, Plipat, Nottasorn, Sirisanthana, Virat, Prasitsuebsai, Wasana, Hongsiriwan, Suchat, Chotpitayasunondh, Tawee, Eksaengsri, Achara, Toye, MariPat, Smith, Mary Elizabeth, McIntosh, Kenneth, Capparelli, Edmund, Yogev, Ram
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981099/
https://ncbi.nlm.nih.gov/pubmed/20453709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0b013e3181e2189d
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