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Use of yeast artificial chromosome clones for mapping and walking within human chromosome segment 18q21.3.

Well-characterized large genomic clones obtained from yeast artificial chromosome (YAC) libraries provide the framework to localize genes and approach genetic disease. We developed universally applicable approaches to establish authenticity, localize and orient internal genes, map restriction sites,...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Silverman, G A, Ye, R D, Pollock, K M, Sadler, J E, Korsmeyer, S J
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298089/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2678105/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.19.7485
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