Improved protection against avian influenza H5N1 virus by a single vaccination with virus-like particles in skin using microneedles

To develop a more effective vaccination method against H5N1 virus, we investigated the immunogenicity and protective efficacy after skin vaccination using microneedles coated with influenza virus-like particles containing hemagglutinin derived from A/Vietnam/1203/04 H5N1 virus (H5 VLPs). A single mi...

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Detalhes bibliográficos
Main Authors: Song, Jae-Min, Kim, Yeu-Chun, Barlow, Peter G., Hossain, M. Jaber, Park, Kyoung-Mi, Donis, Ruben O., Prausnitz, Mark R., Compans, Richard W., Kang, Sang-Moo
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980851/
https://ncbi.nlm.nih.gov/pubmed/20851715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2010.09.001
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