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Activation of Nanoscale Allosteric Protein Domain Motion Revealed by Neutron Spin Echo Spectroscopy

NHERF1 is a multidomain scaffolding protein that assembles signaling complexes, and regulates the cell surface expression and endocytic recycling of a variety of membrane proteins. The ability of the two PDZ domains in NHERF1 to assemble protein complexes is allosterically modulated by the membrane-...

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Detalhes bibliográficos
Main Authors: Farago, Bela, Li, Jianquan, Cornilescu, Gabriel, Callaway, David J.E., Bu, Zimei
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980739/
https://ncbi.nlm.nih.gov/pubmed/21081097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.09.058
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