TRB3 is stimulated in diabetic kidneys, regulated by the ER stress marker CHOP, and is a suppressor of podocyte MCP-1

The prevalence of diabetic nephropathy continues to rise, highlighting the importance of investigating and discovering novel treatment strategies. TRB3 is a kinase-like molecule that modifies cellular survival and metabolism and interferes with signal transduction pathways. Herein, we report that TR...

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Hauptverfasser: Morse, Elizabeth, Schroth, Jana, You, Young-Hyun, Pizzo, Donald P., Okada, Shinichi, RamachandraRao, Satish, Vallon, Volker, Sharma, Kumar, Cunard, Robyn
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980398/
https://ncbi.nlm.nih.gov/pubmed/20660016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00236.2010
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