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Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase.

Neutrophil NADPH oxidase is a multicomponent enzyme that is activated to generate superoxide anion and is defective in the cells of patients with chronic granulomatous disease. It requires both membrane and cytosolic components, the latter including 47- and 67-kDa proteins recognized by the polyclon...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Volpp, B D, Nauseef, W M, Donelson, J E, Moser, D R, Clark, R A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298023/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2550933/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.18.7195
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