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Targeted correction of a major histocompatibility class II E alpha gene by DNA microinjected into mouse eggs.

DNA molecules containing the 5' end of a functional major histocompatibility class II E alpha gene were injected into mouse eggs bearing E alpha genes with 630-base-pair (bp) deletions encompassing the promoter and first exon. The deletion was corrected by homologous recombination in 1 of about...

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Bibliografski detalji
Glavni autori: Brinster, R L, Braun, R E, Lo, D, Avarbock, M R, Oram, F, Palmiter, R D
Format: Artigo
Jezik:Inglês
Izdano: 1989
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC297999/
https://ncbi.nlm.nih.gov/pubmed/2506546
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