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Microinjection of antisense c-mos oligonucleotides prevents meiosis II in the maturing mouse egg.

Injection of antisense oligonucleotides was used to investigate the function of c-mos in murine oocytes. Oocytes injected with antisense c-mos oligonucleotides completed the first meiotic division but failed to initiate meiosis II. Instead, loss of c-mos function led to chromosome decondensation, re...

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Published in:Proc Natl Acad Sci U S A
Main Authors: O'Keefe, S J, Wolfes, H, Kiessling, A A, Cooper, G M
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1989
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297988/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2476810/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.18.7038
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