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Different 3'-end processing produces two independently regulated mRNAs from a single H1 histone gene.

We describe the isolation of a mouse H1 histone gene that encodes two mRNA transcripts. One mRNA ends just beyond the coding region, near a highly conserved palindrome sequence typical of cell cycle-regulated histone genes. The level of this transcript is coupled to DNA replication. The second mRNA...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Cheng, G H, Nandi, A, Clerk, S, Skoultchi, A I
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297980/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2780558/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.18.7002
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