Site specificity of the inhibitory effects of oligo(nucleoside methylphosphonate)s complementary to the acceptor splice junction of herpes simplex virus type 1 immediate early mRNA 4.

Oligo(nucleoside methylphosphonate)s complementary to the splice junction of herpes simplex virus type 1 immediate early pre-mRNAs 4 and 5 caused specific inhibition of herpes simplex virus type 1 growth. The dodecamer d(TpTCCTCCTGCGG) (deoxynucleoside methylphosphonate residues in italic) caused 50...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kulka, M, Smith, C C, Aurelian, L, Fishelevich, R, Meade, K, Miller, P, Ts'o, P O
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297951/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2550925/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.18.6868
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