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Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein.

The principal neutralizing determinant of human immunodeficiency virus type 1 (HIV-1) is located in the external envelope protein, gp120, and has previously been mapped to a 24-amino acid-long sequence (denoted RP135). We show here that deletion of this sequence renders the envelope unable to elicit...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Javaherian, K, Langlois, A J, McDanal, C, Ross, K L, Eckler, L I, Jellis, C L, Profy, A T, Rusche, J R, Bolognesi, D P, Putney, S D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297927/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2771954/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.17.6768
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