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Expression Level, Evolutionary Rate, and the Cost of Expression

There is great variation in the rates of sequence evolution among proteins encoded by the same genome. The strongest correlate of evolutionary rate is expression level: highly expressed proteins tend to evolve slowly. This observation has led to the proposal that a major determinant of protein evolu...

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Detalhes bibliográficos
Autor principal: Cherry, Joshua L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2979011/
https://ncbi.nlm.nih.gov/pubmed/20884723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evq059
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