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Immunological demonstration of the accumulation of insulin, but not insulin receptors, in nuclei of insulin-treated cells.

Although insulin is known to regulate nuclear-related processes, such as cell growth and gene transcription, the mechanisms involved are poorly understood. Previous studies suggested that translocation of insulin or its receptor to cell nuclei might be involved in some of these processes. The presen...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Soler, A P, Thompson, K A, Smith, R M, Jarett, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297900/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2672001/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.17.6640
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