Loss of STAT1 from Mouse Mammary Epithelium Results in an Increased Neu-Induced Tumor Burden

Type I and type II classes of interferons (IFNs) signal through the JAK/STAT1 pathway and are known to be important in adaptive and innate immune responses and in protection against tumors. Although STAT1 is widely considered a tumor suppressor, it remains unclear, however, if this function occurs i...

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Autori principali: Klover, Peter J, Muller, William J, Robinson, Gertraud W, Pfeiffer, Ruth M, Yamaji, Daisuke, Hennighausen, Lothar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978912/
https://ncbi.nlm.nih.gov/pubmed/21076615
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