Llwytho...

Cholesteryl-conjugated oligonucleotides: synthesis, properties, and activity as inhibitors of replication of human immunodeficiency virus in cell culture.

A family of oligonucleotides and phosphorothioate oligonucleotide analogues was synthesized with a cholesteryl group tethered at the 3'-terminal internucleoside link. This modification, introduced to enhance interaction of the polyanions with cell membranes, significantly increases the antivira...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Letsinger, R L, Zhang, G R, Sun, D K, Ikeuchi, T, Sarin, P S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1989
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC297882/
https://ncbi.nlm.nih.gov/pubmed/2771942
Tagiau: Ychwanegu Tag
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