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The synthetic caged Garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity

Several caged Garcinia xanthone natural products have potent bioactivity and a documented value in traditional eastern medicine. Previous synthesis and SAR studies of these natural products resulted in the identification of the pharmacophore represented by the structure of cluvenone. In the current...

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Detalhes bibliográficos
Main Authors: Batova, Ayse, Altomare, Diego, Chantarasriwong, Oraphin, Ohlsen, Kari L., Creek, Kim E., Lin, You-Chin, Messersmith, Amy, Yu, Alice L., Yu, John, Theodorakis, Emmanuel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978789/
https://ncbi.nlm.nih.gov/pubmed/20881270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0517
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