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Is Slow-Onset Long-Acting Monoamine Transport Blockade to Cocaine as Methadone is to Heroin? Implication for Anti-Addiction Medications

The success of methadone in treating opiate addiction has suggested that long-acting agonist therapies may be similarly useful for treating cocaine addiction. Here, we examined this hypothesis, using the slow-onset long-acting monoamine reuptake inhibitor 31,345, a trans-aminotetralin analog, in a v...

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Autori principali: Peng, Xiao-Qing, Xi, Zheng-Xiong, Li, Xia, Spiller, Krista, Li, Jie, Chun, Lauren, Wu, Kuo-Ming, Froimowitz, Mark, Gardner, Eliot L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978747/
https://ncbi.nlm.nih.gov/pubmed/20827272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.133
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