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Challenges assessing clinical endpoints in early Huntington disease

The primary aim of this study was to evaluate the current accepted standard clinical endpoint for the earliest-studied HD participants likely to be recruited into clinical trials. Since the advent of genetic testing for HD, it is possible to identify gene carriers prior to the diagnosis of disease,...

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Detalhes bibliográficos
Main Authors: Paulsen, Jane S., Wang, Chiachi, Duff, Kevin, Barker, Roger, Nance, Martha, Beglinger, Leigh, Moser, David, Williams, Janet K., Simpson, Sheila, Langbehn, Douglas, van Kammen, Daniel P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978744/
https://ncbi.nlm.nih.gov/pubmed/20623772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.23337
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