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Inhibition of Endothelin-1-Mediated Contraction of Hepatic Stellate Cells by FXR Ligand
Activation of hepatic stellate cells (HSCs) plays an important role in the development of cirrhosis through the increased production of collagen and the enhanced contractile response to vasoactive mediators such as endothelin-1 (ET-1). The farnesoid X receptor (FXR) is a member of the nuclear recept...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978707/ https://ncbi.nlm.nih.gov/pubmed/21085652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013955 |
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