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Modelling Vesicular Release at Hippocampal Synapses

We study local calcium dynamics leading to a vesicle fusion in a stochastic, and spatially explicit, biophysical model of the CA3-CA1 presynaptic bouton. The kinetic model for vesicle release has two calcium sensors, a sensor for fast synchronous release that lasts a few tens of milliseconds and a s...

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Autori principali: Nadkarni, Suhita, Bartol, Thomas M., Sejnowski, Terrence J., Levine, Herbert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978677/
https://ncbi.nlm.nih.gov/pubmed/21085682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000983
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