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De Novo DNA Methyltransferase DNMT3b Interacts with NEDD8-modified Proteins
DNA methylation and histone modifications play an important role in transcription regulation. In cancer cells, many promoters become aberrantly methylated through the activity of the de novo DNA methyltransferases DNMT3a and DNMT3b and acquire repressive chromatin marks. NEDD8 is a ubiquitin-like pr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978566/ https://ncbi.nlm.nih.gov/pubmed/20847044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155721 |
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