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A new hypothesis on the simultaneous direct and indirect proton pump mechanisms in NADH-quinone oxidoreductase (complex I)

Recently, Sazanov’s group reported the X-ray structure of whole complex I [Nature, 465, 441 (2010)], which presented a strong clue for a “piston-like” structure as a key element in an “indirect” proton pump. We have studied the NuoL subunit which has a high sequence similarity to Na(+)/H(+) antiport...

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Detalhes bibliográficos
Main Authors: Ohnishi, Tomoko, Nakamaru-Ogiso, Eiko, Ohnishi, S. Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978500/
https://ncbi.nlm.nih.gov/pubmed/20816962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.08.039
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