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Cloning and molecular characterization of genes whose products allow Salmonella typhimurium to penetrate tissue culture cells.

Invasion of the intestinal epithelium is thought to be an important step in the pathogenesis of Salmonella infections. Using an in vitro system, we have isolated a genetic locus, inv, that confers to a noninvasive strain of Salmonella typhimurium the ability to penetrate tissue culture cells. Highly...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Galán, J E, Curtiss, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297844/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2548211/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.16.6383
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