Polar/apolar chemical inducers of differentiation of transformed cells: strategies to improve therapeutic potential.

N,N'-Hexamethylenebisacetamide (HMBA) induces transformed cells to differentiate, accompanied by suppression of oncogenicity. Clinical trials have shown that HMBA can cause positive therapeutic responses in some cancer patients, but clinical efficacy may be limited, in part, by dose-related tox...

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Bibliografske podrobnosti
Main Authors: Marks, P A, Breslow, R, Rifkind, R A, Ngo, L, Singh, R
Format: Artigo
Jezik:Inglês
Izdano: 1989
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC297838/
https://ncbi.nlm.nih.gov/pubmed/2762329
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