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Facilitated leaky scanning and atypical ribosome shunting direct downstream translation initiation on the tricistronic S1 mRNA of avian reovirus

The S1 mRNA of avian reovirus is functionally tricistronic, encoding three unrelated proteins, p10, p17 and σC, from three sequential, partially overlapping open reading frames (ORFs). The mechanism of translation initiation at the 3′-proximal σC ORF is currently unknown. Transient RNA transfections...

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Bibliografske podrobnosti
Main Authors: Racine, Trina, Duncan, Roy
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978376/
https://ncbi.nlm.nih.gov/pubmed/20610435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq611
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