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5′-UTR G-quadruplex structures acting as translational repressors

Given that greater than 90% of the human genome is expressed, it is logical to assume that post-transcriptional regulatory mechanisms must be the primary means of controlling the flow of information from mRNA to protein. This report describes a robust approach that includes in silico, in vitro and i...

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Autores principales: Beaudoin, Jean-Denis, Perreault, Jean-Pierre
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978341/
https://ncbi.nlm.nih.gov/pubmed/20571090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq557
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