When simple sequence comparison fails: the cryptic case of the shared domains of the bacterial replication initiation proteins DnaB and DnaD

DnaD and DnaB are essential DNA-replication-initiation proteins in low-G+C content Gram-positive bacteria. Here we use sensitive Hidden Markov Model-based techniques to show that the DnaB and DnaD proteins share a common structure that is evident across all their structural domains, termed DDBH1 and...

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Autors principals: Marston, Farhat Y., Grainger, William H., Smits, Wiep Klaas, Hopcroft, Nicholas H., Green, Matthew, Hounslow, Andrea M., Grossman, Alan D., Craven, C. Jeremy, Soultanas, Panos
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Genome Integrity, Repair and Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978336/
https://ncbi.nlm.nih.gov/pubmed/20587500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq465
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