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Inhibition of 2A-mediated ‘cleavage’ of certain artificial polyproteins bearing N-terminal signal sequences

Where 2A oligopeptide sequences occur within ORFs, the formation of the glycyl-prolyl peptide bond at the C-terminus of (each) 2A does not occur. This property can be used to concatenate sequences encoding several proteins into a single ORF: each component of such an artificial polyprotein is genera...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: de Felipe, Pablo, Luke, Garry A, Brown, Jeremy D, Ryan, Martin D
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: WILEY-VCH Verlag 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978324/
https://ncbi.nlm.nih.gov/pubmed/19946875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.200900134
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